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Ginger (Zingiber officinale Roscoe, Zingiberaceae) is one of the most commonly consumed dietary condiments in the world (Surh et al. 1999). The oleoresin (i.e., oily resin) from the rhizomes (i.e., roots) of ginger contains many bioactive components, such as -gingerol (1-[4′-hydroxy-3′- methoxyphenyl]-5-hydroxy-3-decanone; Figure 7.1), which is the primary pungent ingredient that is ...
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Ginger Taylor in Texas We found 54 records for Ginger Taylor in New Braunfels, League City and 35 other cities in Texas. Select the best result to find their address, phone number, relatives, and …
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Resides in Wenatchee, WA. Cancer Epidemiol Biomarkers Prev. Weidner M. H, Cekanova M, Baek S. M, Pugliese A, editors. In Sections 7. M, Chun K. J, Tran V. Eur J Gastroenterol Hepatol. Results indicated that the free forms of -, -, and -gingerols or -shogaol were not detectable, whereas the respective glucuronide of each compound was detected, suggesting that these ginger components are readily absorbed after oral consumption and can be detected as glucuronide conjugates Zick et al. Frondoza C. Indian J Biochem Biophys. D, Lantz R. These results were supported in a later study in which rats that were given a single intraperitoneal injection of -gingerol 2. Effects of ginger on gastroduodenalmotility. Recent Activity. P, Lokesh B. Ginger ingredients reduce viability of gastric cancer cells via distinct mechanisms. Br J Nutr. Results indicated that ginger and vitamin B6 therapy were equally effective in reducing nausea and the number of vomiting episodes during pregnancy Sripramote and Lekhyananda ; Smith et al. In contrast, patients suffering from osteoarthritis of the knee showed a consistently greater response to treatment with ginger extract compared with the control group Altman and Marcussen The protective action of ethanolic ginger Zingiber officinale extract in cholesterol fed rabbits. Drug Metabol Drug Interact. However, at 6 hours, patients who had received ginger reported significantly less nausea and vomiting than the placebo group Apariman, Ratchanon, and Wiriyasirivej Treating pregnancy-related nausea and vomiting with ginger. H, Roufogalis B. Wang W, Li C. In contrast, larger doses of ginger components inhibited oxygen consumption, which was attributed to disruption of mitochondrial function Eldershaw et al. Effects of ginger on motion sickness susceptibility and gastric function. Includes Address 15 Phone 5 Email 3. These effects were associated with a decreased abundance of cyclin D1 a proto-oncoprotein that is overexpressed in cancer and increased expression of a nonsteroidal anti-inflammatory drug NSAID -activated gene NAG-1 , a proapoptotic and antitumorigenic protein Lee, Cekanova, and Baek Effects of ginger Zingiber officinale Roscoe on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model. Evidence of nutriceutical effectiveness in the treatment of osteoarthritis. The effectiveness of ginger has been compared with that of vitamin B6 another recommended therapy in randomized, double-blind, controlled trials. Ginger is recognized by the U. Chen B. Resides in Center, TX. Resides in Bolinas, CA. Review Some phytochemical, pharmacological and toxicological properties of ginger Zingiber officinale Roscoe : a review of recent research. This compound showed weaker pungency but more potent antiulcer activity than -gingerol or -shogaol Yoshikawa et al. S, Kim J, Lee K. Related To Daniel Polakoff. P, Timmermann B. J Travel Med. Again, mechanisms are lacking, but no reports indicate that ginger has any adverse side effects or that it can worsen illness in pregnant women or patients. V, Pandi P. J Clin Invest. J, Lee S. Talalay P, Talalay P. Resides in Warner Robins, GA.
NCBI Bookshelf. Herbal Medicine: Biomolecular and Clinical Aspects. Ann M. Bode and Zigang Dong. More and more older adults i. However, this might not be a safe or advisable practice. For example, at least one recent survey revealed a significant problem with herb-chemotherapeutic drug interactions in cancer patients and, notably, at least half of the herbal remedies taken by these patients lacked research data documenting their potential interactions Engdal, Klepp, and Nilsen Regrettably, a great deal of the information regarding the effectiveness and safety of these remedies has been garnered from anecdotal or historical accounts, and much of the information offered is generally misleading and might even be detrimental Ernst and Schmidt Ginger Zingiber officinale Roscoe, Zingiberaceae is one of the most commonly consumed dietary condiments in the world Surh et al. The oleoresin i. Although ginger is generally considered to be safe Kaul and Joshi , the lack of a complete understanding of its mechanisms of action suggests caution in its therapeutic use Wilkinson a. Previous reviews Barrett, Kiefer, and Rabago ; Ness, Sherman, and Pan ; Talalay and Talalay have emphasized the importance of careful scientific research in establishing the safety and efficacy of potential therapeutic plant remedies and in defining the risks and benefits of herbal medicine. Ginger has been used for thousands of years for the treatment of numerous ailments, such as colds, nausea, arthritis, migraines, and hypertension. The medicinal, chemical, and pharmacological properties of ginger have been extensively reviewed Surh, Lee, and Lee ; Ernst and Pittler ; Afzal et al. Structure of -gingerol, believed to be the most abundant bioactive component of ginger root. Ginger is a member of a plant family that includes cardamom and turmeric. Its spicy aroma is mainly due to presence of ketones, especially the gingerols, which appear to be the primary component of ginger studied in much of the health-related scientific research. The rhizome, which is the horizontal stem from which the roots grow, is the main portion of ginger that is consumed. In Greek, it was called ziggiberis , and in Latin, zinziberi. Interestingly, ginger does not grow in the wild and its actual origins are uncertain. Indians and Chinese are believed to have produced ginger as a tonic root for over years to treat many ailments, and this plant is now cultivated throughout the humid tropics, with India being the largest producer. Ginger was used as a flavoring agent long before history was formally recorded. It was an exceedingly important article of trade and was exported from India to the Roman Empire over years ago, where it was especially valued for its medicinal properties. Ginger continued to be a highly sought after commodity in Europe even after the fall of the Roman Empire, with Arab merchants controlling the trade in ginger and other spices for centuries. In the thirteenth and fourteenth centuries, the value of a pound of ginger was equivalent to the cost of a sheep. By medieval times, it was being imported in preserved form to be used in sweets. Queen Elizabeth I of England is credited with the invention of the gingerbread man, which became a popular Christmas treat. Ginger is used in numerous forms, including fresh, dried, pickled, preserved, crystallized, candied, and powdered or ground. The flavor is somewhat peppery and slightly sweet, with a strong and spicy aroma. The concentration of essential oils increases as ginger ages and, therefore, the intended use of the rhizome determines the time when it is harvested. If extracting the oil is the main purpose, then ginger can be harvested at 9 months or longer. Ginger is commonly pickled in sweet vinegar, which turns it a pink color; this form is popular with sushi. Ginger harvested at months has a tough skin that must be removed before eating, and the root is more pungent and is used dried or pulverized into ground ginger. This is the form most commonly found in our spice racks and used in cookies, cakes, and curry mixes. Candied or crystallized ginger is cooked in sugar syrup and coated with granulated sugar. Ginger harvested at 5 months is not yet mature and has a very thin skin, and the rhizomes are tender with a mild flavor and are best used in fresh or preserved forms. At least constituents in fresh and dried ginger varieties have been identified by a variety of analytical processes. Gingerols are the major constituents of fresh ginger and are found slightly reduced in dry ginger, whereas the concentrations of shogaols, which are the major gingerol dehydration products, are more abundant Jolad et al. At least 31 gingerol-related compounds have been identified from the methanolic crude extracts of fresh ginger rhizome Jiang, Solyom et al. The proportion of each individual component in a sample of ginger depends on country of origin, commercial processor, and whether the ginger is fresh, dried, or processed Schwertner, Rios, and Pascoe Of the bioactive pungent components of Jamaican ginger, including -, -, and -gingerols and -shogaol, -gingerol appears to be the most abundant pungent bioactive compound in most of the oleoresin samples studied Bailey-Shaw et al. Although phylogenetic analysis has showed that all ginger samples from widely different geographical origins are genetically indistinguishable, metabolic profiling showed some quantitative differences in the contents of -, -, and -gingerols Jiang et al. An examination of the concentrations of -, -, and -gingerols and -shogaol in 10 different ginger-root dietary supplements purchased randomly from a variety of pharmacies and health food stores yielded some disconcerting results Schwertner, Rios, and Pascoe Perhaps not surprisingly, the content of these active components was found to vary extensively from none or very minute amounts to several milligrams per gram. In addition, the suggested serving size ranged from about mg to 4. The basis for the wide range of dosing is not clear. These studies suggest that ginger contains a variety of bioactive compounds and standardization of contents is critically lacking. Although ginger is one of the most widely consumed spices in the world, not a great deal is known regarding its metabolism or metabolites. Evaluating the bioactivity of ginger is necessary for completely understanding its mechanism of action and potential therapeutic effects.
Ghayur M. T, Pan C. Qian Q. Fugh-Berman A, Kronenberg F. S, Kundu J. A survey of a group of obstetricians and gynecologists revealed that most of them would recommend taking an antiemetic Ginger's Zingiber officinale Roscoe inhibition of rat colonic adenocarcinoma cellsproliferation and angiogenesis in vitro. C, Liao J. Options for the prevention and management of acute chemotherapy- induced nausea and vomiting in children. A systematic screening of total antioxidants in dietary plants. Review Ginger--an herbal medicinal product with broad anti-inflammatory actions. Eur J Gastroenterol Hepatol. Cancer chemotherapy-induced nausea and vomiting: Role of mediators, development of drugs and treatment methods. Kaul P. Nicoll R, Henein M. H, Wu P. Zingiber officinale. An examination of the concentrations of -, -, and -gingerols and -shogaol in 10 different ginger-root dietary supplements purchased randomly from a variety of pharmacies and health food stores yielded some disconcerting results Schwertner, Rios, and Pascoe Although many food-derived supplements are consumed today with little knowledge of their activity or safety, more attention is beginning to be given to addressing these issues. J, Potter P. Y, Liu T. Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. In this case, human volunteers were given ginger at doses ranging from mg to 2 g and blood samples were taken at 15 minutes to 72 hours after a single oral dose. E, Akcay A. Interestingly, ginger does not grow in the wild and its actual origins are uncertain. Also known as Candace Ginger Taylor. G, Koch S. In particular, -gingerol has been reported to be highly effective as an anticancer agent in skin in vivo in the two-stage initiation-promotion mouse skin model. Antiplatelet therapy is an effective approach for preventing coronary heart disease. This compound also inhibited proliferation of several transgenic mouse ovarian cancer cell lines, including C1 and C2 Kim et al. Effect of -gingerol on pro-inflammatory cytokine production and costimulatory molecule expression in murine peritoneal macrophages. Int J Clin Pharmacol Ther. Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger. Plasma pharmacokinetics and tissue distribution of -gingerol in rats. Related To Daniel Polakoff. M, Surh Y. Resides in Tulsa, OK. Y, Hsieh W. J Nat Prod. Ginger prevents Th2-mediated immune responses in a mouse model of airway inflammation. In addition, blocking the tumor promoter—induced activation of AP-1 inhibited neoplastic transformation Dong et al. Arch Facial Plast Surg. Resides in Morristown, NJ. Jiang X, Williams K. Multiple mechanisms are involved in -gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Y, Li Y.
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